In the 1980s, the American Dietetic Association banned gluten-free diets in the U.S., but the FDA hasn’t been able to stop the practice.
Since then, people have been consuming gluten-containing foods in the United States.
Now, a new study published in the journal Cell Metabolism suggests that a person who doesn’t eat the gluten-based foods can have the condition.
Researchers found that those who ate the gluten in the diet for a year did not develop celiac, but the diet itself was linked to increased risk.
“It’s not just that it doesn’t happen,” said lead researcher Dr. Rami Salah, of the University of Washington School of Medicine.
“But the fact that it happens does not mean it’s harmless.”
This new study has the potential to have a huge impact on celiac patients.
The results suggest that celiac can be cured with lifestyle changes.
The new study used a population of people with celiac who were living with other medical conditions.
Researchers looked at the gene responsible for the autoimmune response and the other genetic variants that can trigger the autoimmune disease.
Salah said they found that people with genetic variants in the G1-TAC2TAC1C1TAC3 gene were more likely to develop celias.
“We found that these people had been on a gluten- and dairy-free diet for one year and the next year their levels of circulating TAC-3 went up and their circulating T3 went down,” Salah told CBS News.
The researchers also found that if people were on a low-carbohydrate diet, they had lower levels of the TAC2 receptor, and so they were more at risk for developing the disease.
The study also found the most common genetic variant to be a single copy of the G4-TAT1 gene.
Salh and his colleagues are now working on using a protein called TAC to mimic the genetic changes in the TAT receptor to treat celiac.
“You might think that it’s the other way around.
It’s not the other one,” Salh said.
“If you’ve got a G4 protein, it’s like, you know, that’s just one of the things you do.
But if you have a G1 protein, you’ve gone for a completely different route.”
It’s unclear how this gene variant might affect the other genes involved in the autoimmune reaction, but it could help us understand how other genetic mutations could affect celiac and others with celias, Salah explained.
“In terms of how the T1-C2 gene works, it might be involved in other autoimmune disorders like Crohn’s disease, diabetes, or type 1 diabetes,” he said.
In the future, Sala said, scientists hope to look at other genetic variations in people with these autoimmune conditions.
“I hope to be able to do this in other people, but we’re only beginning,” Sala told CBS.
“The most important thing right now is to try to prevent people from getting it in the first place.
We don’t know what the impact might be, but I think that this study has made it much easier for people to avoid the gluten.
If we don’t do anything to prevent the development of this autoimmune disease, then it will go unchecked.”
The National Institutes of Health is one of several government agencies funding the study.